我們都希望COVID-19疫苗即將問世，但全球冷鏈必須做好準(zhǔn)備，在全世界分發(fā)這些疫苗。中國這次成為了全球疫苗的研發(fā)和生產(chǎn)基地。

這是一項(xiàng)史無前例的任務(wù)，在廣闊的地理區(qū)域有大量的樞紐。疫苗可能必須從生產(chǎn)設(shè)施運(yùn)送到儲(chǔ)存和分發(fā)中心，然后再運(yùn)送到醫(yī)療設(shè)施進(jìn)行當(dāng)?shù)毓芾砘蚶洳亍?             

確定潛在COVID-19疫苗的溫度要求。      

目前，科學(xué)界對(duì)COVID-19疫苗的潛在脆弱性或穩(wěn)定性還沒有達(dá)成共識(shí)。然而，全球都在努力開發(fā)疫苗。          

這鼓勵(lì)研究人員探索以前從未被批準(zhǔn)用于疫苗的新技術(shù)，包括冠狀病毒蛋白質(zhì)的RNA編碼。

We all hope that the covid-19 vaccine will be available soon, but the global cold chain must be ready to distribute these vaccines around the world. China has become a global vaccine research and development and production base.            

This is an unprecedented task with a large number of hubs in a vast geographical area. Vaccines may have to be transported from production facilities to storage and distribution centers, and then to medical facilities for local management or refrigeration.            

Determine the temperature requirements for a potential covid-19 vaccine.           

At present, the scientific community has not reached a consensus on the potential vulnerability or stability of covid-19 vaccine. However, efforts are being made around the world to develop vaccines.            

This encourages researchers to explore new technologies that have never been previously approved for use in vaccines, including RNA coding of coronavirus proteins.

這意味著關(guān)鍵信息，如潛在疫苗的溫度耐受范圍，在很大程度上仍然是未知的。從現(xiàn)有數(shù)據(jù)來看，一些潛在的疫苗可能需要+2到+8.C的溫度范圍，而另一些可能需要-80.C的溫度范圍。               

由于世界衛(wèi)生組織和國際航空運(yùn)輸協(xié)會(huì)都指出，由于溫度控制不當(dāng)造成的疫苗浪費(fèi)每年約為25%，因此COVID-19冷鏈的物流故障可能代價(jià)高昂。              

物流合作伙伴必須能夠制定全面的應(yīng)急措施，確保在任何特定地點(diǎn)和時(shí)間通過快速補(bǔ)充冷卻劑來保護(hù)冷鏈。  迅速將疫苗運(yùn)送到經(jīng)過認(rèn)證的溫控儲(chǔ)存設(shè)施，以管理任何運(yùn)輸延誤。        

估計(jì)疫苗數(shù)量、材料尺寸、海關(guān)要求和旅途中所有地點(diǎn)的外部溫度是一個(gè)詳盡的過程。這不僅需要對(duì)物流有全面的了解，還需要疫苗穩(wěn)定性方面的專業(yè)知識(shí)。 利用專業(yè)的后勤支持管理未知事物，雖然在許多問題得到回答之前無法設(shè)計(jì)出最佳解決方案，但保證任何潛在疫苗在其旅程中的每一點(diǎn)都保持在其基本溫度范圍內(nèi)是至關(guān)重要的。              

目前，供應(yīng)鏈在應(yīng)對(duì)COVID-19的影響方面面臨著巨大的壓力。要找到一種穩(wěn)定、符合質(zhì)量保證標(biāo)準(zhǔn)、能夠安全和全球分發(fā)的COVID-19疫苗，需要制造、醫(yī)療、物流和監(jiān)管專家的全球合作。

This means that key information, such as the temperature tolerance range of potential vaccines, remains largely unknown. From the available data, some potential vaccines may require a temperature range of + 2 to + 8. C, while others may require a temperature range of - 80. C.            

As the World Health Organization and the International Air Transport Association point out that the vaccine waste caused by improper temperature control is about 25% per year, the logistics failure of covid-19 cold chain may be costly.            Logistics partners must be able to develop comprehensive emergency measures to ensure that the cold chain is protected by rapid coolant replenishment at any given location and time. Quickly deliver vaccines to certified temperature controlled storage facilities to manage any transport delays.            

Estimating vaccine quantities, material sizes, customs requirements and external temperatures at all locations during the trip is a detailed process. This requires not only a comprehensive understanding of logistics, but also expertise in vaccine stability. Using professional logistics support to manage the unknown, although it is impossible to design the best solution until many questions are answered, it is essential to ensure that any potential vaccine stays within its basic temperature range at every point in its journey.            

At present, the supply chain is facing great pressure in response to the impact of covid-19. To find a stable, quality assurance compliant, safe and globally distributed covid-19 vaccine requires the global collaboration of manufacturing, medical, logistics and regulatory experts.